Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.
It is a major cause of morbidity and mortality in children and adults. Septic shock is subset of sepsis in which profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone. About three quarters of cases of sepsis derive from community-acquired infection, and not infrequently present to general practice. The GP has a critical role to identify and manage patients with sepsis. Sepsis (262 downloads)