Lymphadenopathy is defined by lymph nodes that are abnormal either in size, consistency or number. While the majority of patients presenting to the GP have benign lymphadenopathy, enlarged lymph nodes can be associated with malignancy or other serious causes. Hence, it is vital to develop a structured approach to assessment of lymphadenopathy to avoid under- or over-investigation. The focus of registrar teaching should be to identify red flags, differentiate between benign versus malignant presentations, and apply a rational approach to test ordering.
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